Encouraging Market-Shaping Approaches to Global Problems

The success of Operation Warp Speed in 2020, which brought forth an effective COVID-19 vaccine in less than twelve months, was not only a scientific breakthrough but also a demonstration of the power of an approach called an advanced market commitment (AMC). By creating a demand so that pharmaceutical companies could invest in production prior to proving the efficacies of vaccines, this successful approach accelerated time to market and highlighted the opportunity for a class of similar “market-shaping tools” to accelerate progress. To expand this approach, Griffin Catalyst and Schmidt Futures have partnered with the University of Chicago to launch a first-of-its-kind market accelerator program to surface and support the next great market-shaping solutions, while teaching policymakers to use these techniques to address complex challenges.
Photo Credit: Photo by Ava Gomez, Becker Friedman Institute for Economics at the University of Chicago
On May 4, 2023, the University of Chicago launched its new Market-Shaping Accelerator at an event in Washington, D.C. Participants above included (left to right) Christopher Snyder, Michael Kremer, Jean Tirole, and Susan Athey.

As the pandemic worsened in the United States, Ken Griffin worked with senior U.S. officials and championed the idea of early manufacture and production of vaccines and treatments to accelerate time to market. This extraordinary effort led to the development of a mass-produced, effective, and safe vaccine for COVID-19 in record time, saving hundreds of thousands-if not millions-of lives. The initiative also demonstrated the potential of an exciting but underused approach to innovation: the use of market-shaping approaches —such as advance market commitments, milestone payments, and competitive prizes—to catalyze private investment toward a public good.

Yet for all its potential, market-shaping approaches remain largely unused—in part because the knowledge required to design and launch these initiatives remains siloed among a handful of institutions and individuals, and in part because of a lack of design and advocacy efforts for multi-year market interventions.  Despite its demonstrated success, the technique has not entered the “toolbox” of federal or other government agencies.

How It Works

The market-shaping approach has played a vital role in a variety of recent advances.  NASA uses milestone payments in its work with new private partners such as SpaceX. The Bill and Melinda Gates Foundation deployed an advanced market commitment to create a pneumococcal vaccine which to date has saved over 700,000 lives, and Stripe Climate used an advanced market commitment to develop new techniques for carbon capture.  Griffin Catalyst has itself used market-shaping approaches, such as competitions and prizes, including in its work with The Michael J. Fox Foundation to speed the development of neuro-imaging to identify the presence of Parkinson’s disease.

Despite their differing goals, these achievements all share the same broad approach.  First, public groups and private companies work collaboratively to identify a difficult but well-defined problem (getting a COVID-19 vaccine into people’s arms in less than twelve months, for example), define the terms of success, and, most importantly, introduce an economic incentive (such as an advance purchase commitment by the government or a philanthropy) to encourage the private sector to solve a challenge to the benefit of the larger public.

Who We’re Supporting

With a gift of $4.5 million — alongside Schmidt Futures and facilitated by the Digital Harbor Foundation –  Griffin Catalyst recently supported the launch of a Market-Shaping Accelerator program at the University of Chicago, along with complementary activities to support the use of these approaches.

The program is led by Michael Kremer, University Professor in the Kenneth C. Griffin Department of Economics and joint winner of the 2019 Nobel Prize in Economics; Rachel Glennerster, the former Chief Economist at the Foreign Commonwealth & Development Office in the United Kingdom and former executive director of Jameel Poverty Action Lab at MIT; and by Christopher Snyder, the Joel Z. and Susan Hyatt Professor in Economics at Dartmouth College. Its programs are carried out in partnership with the Federation for American Scientists and the non-profit group 1Day Sooner.

The program pairs promising new proposals for applications of market-shaping ideas, starting with pandemic preparedness and climate, with winners receiving funding to continue to pursue their work.  The program also supports and advises teams as they design their specific market-shaping mechanisms.

To this end, this initiative will also include a market-shaping course at the University of Chicago, accompanied by a Massive Open Online Course and associated open-source materials with global distribution, intended to inspire the next generation of market-shaping efforts.

Why It Matters

As the inspiring success of Operation Warp Speed demonstrated, market-shaping techniques hold promise for practical solutions to many of today’s most difficult and seemingly intractable problems. This initiative aims to widen the use and impact of market-shaping techniques, while also training policymakers to understand and support these underused tools.

The Market-Shaping Accelerator 2023 Innovation Challenge has already shown the importance of this goal. Beyond advancing society’s capacity to respond to future viral pandemics, Phase I winners— comprising 39 teams from 16 different countries worldwide —received support to develop clean generators for low- and middle-income countries, cost-effective respirators, and energy-efficient desalination systems, among others.

These approaches are also starting to get serious attention from the government. The U.S. Department of Energy recently announced $1 billion of funding for the use of this approach to promote clean hydrogen deployment, and the Biden administration announced Project NextGen, a $5 billion effort to “succeed Operation Warp Speed with a mission to develop next-generation vaccines and therapies,” per The Washington Post.

To drive solutions at scale to challenges facing communities around the world, investing in market-shaping mechanisms leverages enterprise and entrepreneurship to deliver meaningful solutions.

Share

IN BRIEF

May 31, 2024
Launched in 2023, the Miami-Dade Innovation Authority leverages the power of competition and innovation to support start-ups, scale solutions to local problems, and improve lives.
October 28, 2024
Griffin Catalyst provided a seed gift of $2.5 million to accelerate the efforts of Feng Zhang, a faculty member at the Broad Institute of MIT and Harvard, to develop “programmable therapeutics,” an approach that holds promise for revolutionizing medicine by reprogramming cells to cure a wide range of human diseases.
June 17, 2025
How did the end of the Age of Dinosaurs in Africa impact world history? That’s what researchers aim to uncover during a five-year project of excavation and analysis in the Northern Cape region of South Africa. Their study will explore fossil ecosystems and the biodiversity of sub-Saharan Africa during the Late Cretaceous Period to dramatically expand scientists’ currently limited understanding of this important epoch.
April 17, 2025
Griffin Catalyst is proud to partner with the nonprofit American History Unbound. The collaboration will present dramatic multimedia storytelling about World War I and World War II to audiences in New York and Miami, and nationwide through a documentary being filmed for broadcast on public television later this year, to coincide with Veterans Day. The unique combination of narration and imagery from renowned historian John Monsky, accompanied by music from Broadway stars and the Orchestra of St. Luke’s, brings to life in new ways two of the most pivotal events in the 20th century.
August 30, 2024
Since 2023, Griffin Catalyst has announced transformative gifts to three major health care institutions in Miami. Taken together, the support—totaling $125 million—represents an investment in the future of medical care and research in South Florida.
May 23, 2024
To pay tribute to the nation's most distinguished military heroes—and to unite our country around the values their stories represent—Griffin Catalyst is supporting the National Medal of Honor Museum Foundation with a $30 million gift. The National Medal of Honor Griffin Institute is a key component of a three-pronged, $300 million effort that also includes a new museum in Arlington, Texas, and a new monument in Washington, D.C.
May 20, 2024
In December 2023, Griffin Catalyst and the David Geffen Foundation announced a gift of $400 million to New York's Memorial Sloan Kettering Cancer Center (MSK), one of the most renowned and advanced cancer research and treatment institutions in the world. This landmark gift—the largest donation to the institution in its nearly 150-year history—will allow MSK to significantly expand and upgrade its research, educational, and treatment facilities toward a singular goal: eradicating cancer.
February 12, 2024
The Lincoln Memorial has long been one of America’s most visited monuments and the scene of some of the defining moments of the last century. In time for the 250th anniversary of the country, a new expansion project will transform a massive, long-hidden space beneath the Lincoln Memorial on the National Mall into an immersive museum, exhibition, and theater space, encouraging visitors to explore the story of one of America’s greatest presidents, Abraham Lincoln, and to learn about the nation’s progress toward becoming a more perfect union.
November 14, 2023
Griffin Catalyst is supporting a major enhancement of UK Biobank, one of the world’s leading scientific resources for health data and biological samples. Griffin Catalyst’s $10 million gift—matched by Eric Schmidt and Schmidt Futures—will enable UK Biobank and scientists from around the world to accelerate research into disease mechanisms, to better leverage artificial intelligence, and to work towards more personalized options for treatment.